Lacicard
Tablet
Generic Name
Lacidipine
Strength
2 mg
Manufacturer
Aristopharma Ltd.
Unit Price
Unit Price: ৳ 4.00 (6 x 10: ৳ 240.00) Strip Price: ৳ 40.00
🔹 Indications
Lacicard is indicated for the treatment of hypertension, either alone or in combination with other antihypertensive agents such as beta-blockers and diuretics.
🔹 Pharmacology
Lacidipine inhibits the influx of calcium into smooth muscle cells by the competitive inhibition of voltage-dependent calcium 'L' channels. This action results in the inhibition of the effects triggered by the influx of calcium into the cells, such as the activation of the contractile proteins in smooth muscle.
🔹 Dosage & Administration
Initially 2 mg as a single daily dose, preferably in the morning; increased after 3-4 weeks to 4 mg daily, then if necessary to 6 mg.
🔹 Interaction
Cimetidine increases the concentration of Lacicard. Lacicard increases the concentration of Digoxin & Propranolol but Propranolol decreases the maximum concentration & AUC of Lacicard.
🔹 Contraindications
Hypersensitivity to dihydropyridine derivatives. Cardiogenic shock, aortic stenosis, avoid within 1 month of myocardial infarction, impaired left ventricular function, pregnancy and breast-feeding.
🔹 Side Effects
Flushing, palpitation, edema, headache, dizziness, rarely gastro-intestinal disturbances, gum hyperplasia, aggravation of angina, mood disturbances, asthenia, polyuria, muscle cramps, skin rash (including pruritus and erythema).
🔹 Pregnancy & Lactation
Use in neonates: There are no data on safety or efficacy of Lacidipine in neonates.
Use in children: Treatment with Lacidipine have not been evaluated in Children.
Use in nursing mothers: Milk transfer studies showed that Lacidipine is excreted into breast milk and therefore, Lacidipine should not be used during lactation.
Use in pregnancy: Although no teratogenic effect of Lacidipine has been established in animals, there are no data on the safety of Lacidipine in human pregnancy; therefore it is contraindicated.
Use in children: Treatment with Lacidipine have not been evaluated in Children.
Use in nursing mothers: Milk transfer studies showed that Lacidipine is excreted into breast milk and therefore, Lacidipine should not be used during lactation.
Use in pregnancy: Although no teratogenic effect of Lacidipine has been established in animals, there are no data on the safety of Lacidipine in human pregnancy; therefore it is contraindicated.
🔹 Precautions & Warnings
Cardiac conduction abnormalities, poor cardiac reserve, hepatic impairment, withdraw if ischemic pain occurs shortly after initiating treatment or if cardiogenic shock develops, avoid grapefruit juice (may affect metabolism).
🔹 Storage Conditions
Store in a cool and dry place, protect from light and moisture. Keep out of the reach of children.
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💡 Frequently Asked Questions
Lacicard is indicated for the treatment of hypertension, either alone or in combination with other antihypertensive agents such as beta-blockers and diuretics.
Initially 2 mg as a single daily dose, preferably in the morning; increased after 3-4 weeks to 4 mg daily, then if necessary to 6 mg.
Flushing, palpitation, edema, headache, dizziness, rarely gastro-intestinal disturbances, gum hyperplasia, aggravation of angina, mood disturbances, asthenia, polyuria, muscle cramps, skin rash (including pruritus and erythema).
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